CRYSTAL-STRUCTURES AND PHARMACOLOGIC ACTIVITIES OF 1,4-DIHYDROPYRIDINE CALCIUM-CHANNEL ANTAGONISTS OF THE ISOBUTYL METHYL 2,6-DIMETHYL-4-(SUBSTITUTED PHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE (NISOLDIPINE) SERIES

被引：76

作者：

FOSSHEIM, R

JOSLYN, A

SOLO, AJ

LUCHOWSKI, E

RUTLEDGE, A

TRIGGLE, DJ

机构：

[1] SUNY BUFFALO,SCH PHARM,DEPT BIOCHEM PHARMACOL,BUFFALO,NY 14260

[2] SUNY BUFFALO,SCH PHARM,DEPT MED CHEM,BUFFALO,NY 14260

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 02期

关键词：

D O I：

10.1021/jm00397a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：300 / 305

页数：6

共 34 条

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[7] CRYSTAL-STRUCTURE OF THE CALCIUM-CHANNEL ANTAGONIST - 3,5-BIS(METHOXYCARBONYL)-2,6-DIMETHYL-4-(2-TRIFLUOROMETHYLPHENYL)-1,4-DIHYDROPYRIDINE
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[8] CRYSTAL-STRUCTURE OF THE DIHYDROPYRIDINE CA-2+ ANTAGONIST FELODIPINE - DIHYDROPYRIDINE BINDING PREREQUISITES ASSESSED FROM CRYSTALLOGRAPHIC DATA
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[9] CRYSTAL-STRUCTURES AND PHARMACOLOGICAL ACTIVITY OF CALCIUM-CHANNEL ANTAGONISTS - 2,6-DIMETHYL-3,5-DICARBOMETHOXY-4-(UNSUBSTITUTED, 3-METHYL-PHENYL, 4-METHYL-PHENYL, 3-NITRO-PHENYL, 4-NITRO-PHENYL, AND 2,4-DINITROPHENYL)-1,4-DIHYDROPYRIDINE
FOSSHEIM, R
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TRIGGLE, DJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (02) : 126 - 131
[10] FOSSHEIM R, 1986, ACTA CHEM SCAND B, V40, P777

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