APPLICATION OF SIMPLISMA FOR THE ASSESSMENT OF PEAK PURITY IN LIQUID-CHROMATOGRAPHY WITH DIODE-ARRAY DETECTION

被引:38
作者
SANCHEZ, FC [1 ]
MASSART, DL [1 ]
机构
[1] FREE UNIV BRUSSELS,CHEMOAC,B-1090 BRUSSELS,BELGIUM
关键词
LIQUID CHROMATOGRAPHY; SIMPLISMA;
D O I
10.1016/0003-2670(94)00283-5
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The application of SIMPLISMA for the investigation of peak purity with liquid chromatography and diode array detection (LC-DAD) is proposed. SIMPLISMA is applied in the chromatographic direction, and is used to detect pure zones in the chromatogram. The performance of SIMPLISMA and of an approach based on the Gram-Schmidt orthogonalization technique are compared.
引用
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页码:331 / 339
页数:9
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