COPPER CYANIDE CATALYZED PALLADIUM COUPLING OF ALPHA-LITHIO AMINES AND ARYL IODIDES

被引：17

作者：

DIETER, RK

LI, SJ

机构：

[1] Howard L. Hunter Chemistry Laboratory, Clemson University, Clemson

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 21期

关键词：

D O I：

10.1016/0040-4039(95)00577-Y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of alpha-aminoalkyllithium reagents with aryl iodides in the presence of catalytic amounts of CuCN and PdCl2(PPh(3))(2) or [(p-MeOC(6)H(4))(3)P]Pd-4 affords 2-aryl substituted amines in modest to good yields. Coupled products are obtained with electron rich aryl iodides and the reaction fails with electron poor aryl halides.

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页码：3613 / 3616

页数：4

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