SEASONAL-VARIATION IN 25-HYDROXYVITAMIN-D AND PARATHYROID-HORMONE CONCENTRATIONS IN HEALTHY ELDERLY PEOPLE

被引：22

作者：

HEGARTY, V

WOODHOUSE, P

KHAW, KT

机构：

[1] Clinical Gerontology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2QQ, F and G Block, Level 2, Hills Road

来源：

AGE AND AGEING | 1994年 / 23卷 / 06期

关键词：

D O I：

10.1093/ageing/23.6.478

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Seasonal variation in serum 25-hydroxyvitamin D and parathyroid hormone concentration was examined longitudinally in 96 community-dwelling men and women aged 65-74 years. Mean 25-hydroxyvitamin D concentration was lowest in winter (22.7 mmol/l) and highest in summer (35.4 mmol/l); mean parathyroid hormone concentration was highest in winter (3.55 pmol/l) and lowest in summer (3.24 pmol/l): these seasonal variations were highly significant (p < 0.0001). Parathyroid hormone concentrations were inversely related to 25-hydroxyvitamin D concentrations (p < 0.0001). Seasonal variation of 25-hydroxyvitamin D and parathyroid hormone concentration is marked in older healthy adults in Britain. Even in summer, mean 25-hydroxyvitamin D concentrations are low; maintaining more optimal vitamin D levels in the general population may have clinical and public health benefits.

引用

页码：478 / 482

页数：5

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