ANTIFUNGAL ARYLTETRALIN LIGNANS FROM LEAVES OF PODOPHYLLUM-HEXANDRUM

被引：36

作者：

ATTAURRAHMAN ^{[1
]}

ASHRAF, M ^{[1
]}

CHOUDHARY, MI ^{[1
]}

HABIBURREHMAN ^{[1
]}

KAZMI, MH ^{[1
]}

机构：

[1] UNIV AZAD JAMMU & KASHIMIR,DEPT CHEM,MUZAFFARABAD 13100,PAKISTAN

来源：

PHYTOCHEMISTRY | 1995年 / 40卷 / 02期

关键词：

PODOPHYLLUM HEXANDRUM; PODOPHYLLACEAE; LEAVES; ARYLTETRALIN LIGNANS; 4'-O-DEMETHYLDEHYDROPODOPHYLLOTOXIN; PICROPODOPHYLLONE; ISOPICROPODOPHYLLONE; DEHYDROPODOPHYLLOTOXIN; ANTIFUNGAL ACTIVITY;

D O I：

10.1016/0031-9422(95)00195-D

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two aryltetralin lignans, 4'-O-demethyldehydropodophyllotoxin and picropodophyllone, which were earlier reported as semi-synthetic products, were isolated from the leaves of Podophyllum hexandrum of Pakistani origin. Two known aryltetralin lignans, isopicropodophyllone and dehydropodophyllotoxin, were also isolated. Structures were identified by spectroscopic methods. The two new lignans showed strong antifungal activity against Epidermophyton floccosum, Curvularia lunata, Nigrospora oryzae, Microsporum canis, Allescheria boydii and Pleurotus ostreatus, while picropodophyllone also showed activity against Drechslera rostrata.

引用

页码：427 / 431

页数：5

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