MANAGEMENT OF CARCINOID-SYNDROME

被引:8
作者
BONOMI, P
HOVEY, C
DAINAUSKAS, JR
SLAYTON, R
WOLTER, J
机构
[1] Department of Internal Medicine, Rush University, Chicago
[2] Department of Radiology, Rush University, Chicago
[3] Department of Pathology, Rush University, Chicago
来源
MEDICAL AND PEDIATRIC ONCOLOGY | 1979年 / 6卷 / 01期
关键词
carcinoid crisis; chemotherapy; prednisone;
D O I
10.1002/mpo.2950060111
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Two patients who had severe carcinoid syndrome are presented. In one patient prednisone relieved symptoms for 20 months, and in the second patient chemotherapy appears to have precipitated fatal carcinoid crisis. Changes in mentation, increased frequency and intensity of flushing, and hypotension indicate increased risk of a chemotherapy induced carcinoid crisis. Since prednisone may produce relatively long control of carcinoid syndrome, it should be tried before chemotherapy in patients who have increased risk of carcinoid crisis. If chemotherapy is given, doses should be decreased by 50%, and patients should be followed closely. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码:77 / 83
页数:7
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