SUBTYPE-H7 INFLUENZA-VIRUSES - COMPARATIVE ANTIGENIC AND MOLECULAR ANALYSIS OF THE HA-GENES, M-GENES, AND NS-GENES

被引：14

作者：

KLIMOV, A

PROSCH, S

SCHAFER, J

BUCHER, D

机构：

[1] NEW YORK MED COLL,VALHALLA,NY 10595

[2] HUMBOLDT UNIV,INST VIROL,O-1086 BERLIN,GERMANY

[3] BUNDESGESUNDHEITSAMT,INST VIRAL ZOONOSES,W-1000 BERLIN 33,GERMANY

来源：

ARCHIVES OF VIROLOGY | 1992年 / 122卷 / 1-2期

关键词：

D O I：

10.1007/BF01321124

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antigenic analysis of the haemagglutinin and matrix protein with corresponding sets of monoclonal antibodies as well as sequence analysis of HA-, M-, and NS-genes were carried out to establish antigenic and genetic relationships between four fowl plague virus (FPV) strains of H7 subtype. The data obtained revealed close genetic relatedness between the oldest known influenza A virus, A/chicken/Brescia/1902 (H7N7), and two FPV strains, A/FPV/Dobson (H7N7) and A/FPV/Weybridge (H7N7). These three strains apparently differ in all genes investigated from the A/FPV/Rostock isolate.

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页码：143 / 161

页数：19

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