PROTEIN-KINASE ACTIVITY OF RAT-BRAIN HEXOKINASE

被引：30

作者：

ADAMS, V

GRIFFIN, LD

GELB, BD

MCCABE, ERB

机构：

[1] BAYLOR UNIV,INST MOLEC GENET,HOUSTON,TX 77030

[2] BAYLOR UNIV,DEPT PEDIAT,HOUSTON,TX 77030

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 177卷 / 03期

关键词：

D O I：

10.1016/0006-291X(91)90652-N

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hexokinase 1 (HK1) purified from rat brain exhibits protein kinase activity, including autophosphorylation and phosphorylation of histone H2A. This protein kinase activity is observed only in the absence of the HK1 carbohydrate substrate, glucose. Analysis of the ATP-binding domains of the mammalian HK1 protein sequences shows significant homology with other mammalian protein kinases. © 1991.

引用

页码：1101 / 1106

页数：6

共 24 条

[1]

ADAMS V, 1991, IN PRESS BIOCH MED M

[2]

ARORA KK, 1988, J BIOL CHEM, V263, P17422

[3] HEXOKINASE OF RAT-BRAIN MITOCHONDRIA - RELATIVE IMPORTANCE OF ADENYLATE KINASE AND OXIDATIVE-PHOSPHORYLATION AS SOURCES OF SUBSTRATE ATP, AND INTERACTION WITH INTRAMITOCHONDRIAL COMPARTMENTS OF ATP AND ADP [J].