CELL-CULTURE ADAPTATION OF ASTROVIRUS INVOLVES A DELETION

被引：47

作者：

WILLCOCKS, MM

ASHTON, N

KURTZ, JB

CUBITT, WD

CARTER, MJ

机构：

[1] UNIV SURREY,SCH BIOL SCI,GUILDFORD GU2 5XH,SURREY,ENGLAND

[2] INST CHILD HLTH,DEPT MICROBIOL,VIRUS LAB,LONDON WC1N 1EH,ENGLAND

[3] JOHN RADCLIFFE HOSP,PUBL HLTH LAB,OXFORD OX3 9DU,ENGLAND

来源：

JOURNAL OF VIROLOGY | 1994年 / 68卷 / 09期

关键词：

D O I：

10.1128/JVI.68.9.6057-6058.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Astroviruses have been adapted to culture by serial blind passage in primary human embryo cells. All viruses thus adapted possess a 45-nucleotide deletion relative to fecal viruses or isolates made in CaCo-2 cells; this deletion may be responsible for the change in host cell range.

引用

收藏

页码：6057 / 6058

页数：2

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