ADRENERGIC CHANGES DUE TO PERTUSSIS - INSULIN, GLUCOSE AND FREE FATTY ACIDS

被引：14

作者：

TABACHNICK, II

GULBENKIAN, A

机构：

[1] Department of Physiology and Biochemistry, Biological Research Division, Schering Corp., Bloomfield

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1969年 / 7卷 / 02期

关键词：

D O I：

10.1016/0014-2999(69)90009-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Pertussis sensitization increases plasma insulin (IRI) levels and also facilitates insulin release by isoproterenol, norepinephrine, phenylephrine, and theophylline. Further, pertussis reverses epinephrine-induced insulin suppression. The elevated IRI levels are attenuated generally by a β-adrenergic receptor blocker, MJ-1999, and in some instances an α-adrenergic receptor blocker, phenoxybenzamine. Thus, pertussis appears to enhance the β-agonist responsiveness insofar as insulin is concerned.{A table is presented}. © 1969.

引用

页码：186 / +

页数：1