SEMINARS IN THROMBOSIS, THROMBOLYSIS, AND VASCULAR BIOLOGY .2. COAGULATION AND THROMBOSIS

被引：2

作者：

BECKER, RC

机构：

[1] Thrombosis Research Center, University of Massachusetts Medical School, Worcester, MA

来源：

CARDIOLOGY | 1991年 / 78卷 / 03期

关键词：

COAGULATION; THROMBOSIS; CARDIOVASCULAR DISEASE;

D O I：

10.1159/000174792

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hemostatic mechanism is a critical component of a normally functioning circulatory system, preventing life-threatening hemorrhage and assisting in the maintenance of vascular integrity. For longer than half a century, however, nonphysiological intravascular coagulation and thrombosis have been recognized as playing central roles in cardiovascular morbidity and mortality. In order to provide a conceptual framework for the use of antithrombotic therapy, the pathogenetic mechanisms underlying thrombotic events must be clearly understood. The purpose of this review is to define these mechanisms, and discuss the use of anticoagulants in both the prevention and treatment of cardiovascular diseases.

引用

页码：257 / 266

页数：10

共 62 条

[1] ABNORMAL-BLOOD PATHWAYS IN LEFT-VENTRICULAR CAVITY IN ACUTE MYOCARDIAL-INFARCTION - EXPERIMENTAL-OBSERVATIONS WITH SPECIAL REFERENCE TO REGIONAL WALL MOTION ABNORMALITY AND HEMOSTASIS [J].