ENZYME-CATALYZED HYDROLYSIS OF DIMETHYL 7-HYDROXY-3,3-DIMETHYL-2,4-DIOXABICYCLO[3.3.0]OCTANE-6,8-DICARBOXYLATE AND A NOVEL SYNTHESIS OF NEPLANOCIN-A

被引：10

作者：

HUTCHINSON, EJ

ROBERTS, SM

THORPE, AJ

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 18期

关键词：

D O I：

10.1039/p19920002245

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hydrolysis of the diester 1 catalysed by pig liver esterase provided the mono-ester 3. This ester was converted into the amine 9, a precursor of neplanocin 10, thereby confirming the previously proposed configuration of 3.

引用

页码：2245 / 2246

页数：2

共 6 条

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[5] ENZYMES IN ORGANIC-SYNTHESIS .48. PIG-LIVER ESTERASE AND PORCINE PANCREATIC LIPASE CATALYZED HYDROLYSES OF 3,4-(ISOPROPYLIDENEDIOXY)-2,5-TETRAHYDROFURANYL DIESTERS
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