RESOLUTION OF THE ENANTIOMERS OF DRUGS CONTAINING AMINO ALCOHOL STRUCTURE AFTER DERIVATIZATION WITH BROMOACETIC ACID

被引：16

作者：

GUBITZ, G

PIERER, B

WENDELIN, W

机构：

[1] Institute of Pharmaceutical Chemistry, Karl-Franzens-University of Graz, Graz

来源：

CHIRALITY | 1992年 / 4卷 / 05期

关键词：

CHIRAL SEPARATION; LIGAND EXCHANGE CHROMATOGRAPHY; ADRENERGIC DRUGS; BETA-BLOCKERS;

D O I：

10.1002/chir.530040512

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The separation of the enantiomers of drugs containing an amino alcohol structure like adrenergic drugs or beta-blockers is described. The compounds are resolved on chiral ligand-exchange chromatography phases after derivatization with bromoacetic acid.

引用

收藏

页码：333 / 337

页数：5

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