THE USE OF BACTERIOPHAGE-MS2 AS A MODEL SYSTEM TO EVALUATE VIRUCIDAL HAND DISINFECTANTS

被引：32

作者：

JONES, MV ^{[1
]}

BELLAMY, K ^{[1
]}

ALCOCK, R ^{[1
]}

HUDSON, R ^{[1
]}

机构：

[1] LEVER IND DEV & APPLICAT CTR,3600 AA MAARSSEN,NETHERLANDS

来源：

JOURNAL OF HOSPITAL INFECTION | 1991年 / 17卷 / 04期

关键词：

BACTERIOPHAGE-MS2; DISINFECTANT TEST; VIRUCIDE;

D O I：

10.1016/0195-6701(91)90272-A

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A model system which would closely reflect the resistance of poliovirus but could be easily performed in any microbiology laboratory would offer considerable advantages for rapidly screening hand decontamination products. The use of the bacteriophage MS2 as a simple model for virucidal testing has been evaluated. In suspension tests the sensitivity of MS2 to alcohols, organic acids and alkalis generally reflected that observed in studies using poliovirus. MS2 could be applied and recovered from the hands of volunteers with high efficiency. Furthermore MS2 proved to be a suitable replacement for Escherichia coli in a standard hand-decontamination test. © 1991.

引用

页码：279 / 285

页数：7

共 12 条

[1] INVIVO PROTOCOL FOR TESTING EFFICACY OF HAND-WASHING AGENTS AGAINST VIRUSES AND BACTERIA - EXPERIMENTS WITH ROTAVIRUS AND ESCHERICHIA-COLI [J].

ANSARI, SA ;

SATTAR, SA ;

SPRINGTHORPE, VS ;

WELLS, GA ;

TOSTOWARYK, W .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1989, 55 (12) :3113-3118

[2] TEST FOR HYGIENIC HAND DISINFECTION [J].

AYLIFFE, GAJ ;

BABB, JR ;

QUORAISHI, AH .

JOURNAL OF CLINICAL PATHOLOGY, 1978, 31 (10) :923-928

[3] EVALUATION OF VIRUCIDAL COMPOUNDS FOR INACTIVATION OF RHINOVIRUS ON HANDS [J].

HENDLEY, JO ;

MIKA, LA ;

GWALTNEY, JM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1978, 14 (05) :690-694

[4]

Kurtz J B, 1980, J Hosp Infect, V1, P321, DOI 10.1016/0195-6701(80)90008-0

[5]

LENNETTE EH, 1979, DIAGNOSTIC PROCEDURE, P34

[6]

MOLDENHAUER D, 1984, ZBL BAKT MIK HYG B, V179, P544

[7] ACTION OF COMMONLY USED DISINFECTANTS AGAINST ENTEROVIRUSES [J].

NARANG, HK ;

CODD, AA .

JOURNAL OF HOSPITAL INFECTION, 1983, 4 (02) :209-212

[8] EVALUATION OF PROCEDURES FOR HYGIENIC HAND-DISINFECTION - CONTROLLED PARALLEL EXPERIMENTS ON THE VIENNA TEST MODEL [J].

ROTTER, ML ;

KOLLER, W ;

WEWALKA, G ;

WERNER, HP ;

AYLIFFE, GAJ ;

BABB, JR .

JOURNAL OF HYGIENE, 1986, 96 (01) :27-37

[9] ANTIVIRAL ACTIVITY OF AN ALCOHOLIC HAND DISINFECTANT - COMPARISON OF THE INVITRO SUSPENSION TEST WITH INVIVO EXPERIMENTS ON HANDS, AND ON INDIVIDUAL FINGERTIPS [J].

SCHURMANN, W ;

EGGERS, HJ .

ANTIVIRAL RESEARCH, 1983, 3 (01) :25-41

[10] AN EXPERIMENTAL-STUDY ON THE EPIDEMIOLOGY OF ENTEROVIRUSES - WATER AND SOAP WASHING OF POLIOVIRUS-1-CONTAMINATED HANDS, ITS EFFECTIVENESS AND KINETICS [J].

SCHURMANN, W ;

EGGERS, HJ .

MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 1985, 174 (05) :221-236

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