SUCCESSFUL REVERSAL OF NEUTROPENIA IN FELTYS-SYNDROME WITH RECOMBINANT GRANULOCYTE-COLONY-STIMULATING FACTOR

被引：13

作者：

CHOI, MFV

MANT, MJ

TURNER, AR

AKABUTU, J

AARON, SL

机构：

[1] UNIV ALBERTA,WALTER MACKENZIE CTR 2E332,DEPT MED,EDMONTON T6G 2R7,AB,CANADA

[2] UNIV ALBERTA,DEPT PEDIAT,EDMONTON T6G 2S2,AB,CANADA

[3] UNIV ALBERTA HOSP,EDMONTON,AB,CANADA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1994年 / 86卷 / 03期

关键词：

GRANULOCYTE COLONY STIMULATING FACTOR; NEUTROPENIA; FELTYS SYNDROME; RHEUMATOID ARTHRITIS;

D O I：

10.1111/j.1365-2141.1994.tb04805.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report two patients with Felty's syndrome and chronic skin ulcers treated successfully with recombinant granulocyte colony stimulating factor (GCSF). In both cases granulocytes returned to the normal range within days of starting treatment, and their cutaneous ulcers improved. In one patient granulocytes were maintained at normal levels with a regimen of GCSF 3 mu g/kg twice weekly for 14 months.

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收藏

页码：663 / 664

页数：2

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