BIODEGRADATION OF MALACHITE GREEN AND RHODAMINE-B BY CECAL MICROFLORA OF RATS

被引：26

作者：

SINGH, S ^{[1
]}

DAS, M ^{[1
]}

KHANNA, SK ^{[1
]}

机构：

[1] IND TOXICOL RES CTR,DYES & FOOD ADULTERANT TOXICOL LAB,LUCKNOW 226001,UTTAR PRADESH,INDIA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 200卷 / 03期

关键词：

D O I：

10.1006/bbrc.1994.1626

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bio-degradation of two non-permitted dyes namely Malachite green and Rhodamine B. commonly encountered in the food commodities, through rat caecal microflora was studied. Malachite green was biotransformed by caecal microflora to one fluorescent metabolite with a Rf value of 0.09. Incubation of Rhodamine B with caecal microflora resulted in two fluorescent metabolites with Rf values of 0.72 and 0.09. The D150 value of Malachite green was quite low (10 min). while that of Rhodamine B could not be derived as the maximum degradation was only 32%. The results suggest that Malachite green and Rhodamine B are biotransformed to different metabolites by rat caecal microflora which may help in delineating the mechanism of carcinogenic potential of these two dyes. (C) 1994 Academic Press, Inc.

引用

页码：1544 / 1550

页数：7

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