DIRECT APPROACH TO THE DETERMINATION OF THE ROTATIONAL BARRIERS OF THE ACETYLCHOLINE AND CHOLINE MOLECULES

被引：4

作者：

MAKRIYANNIS, A

THEARD, JM

MAUTNER, HG

机构：

[1] TUFTS UNIV,SCH MED,DEPT BIOCHEM PHARMACOL,BOSTON,MA 02111

[2] UNIV CONNECTICUT,INST MAT SCI,STORRS,CT 06268

来源：

BIOCHEMICAL PHARMACOLOGY | 1979年 / 28卷 / 12期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0006-2952(79)90644-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The temperature dependence of the N.M.R. spectra of choline and acetylcholine as well as those of their β-dideutero analogs was investigated. While broadening of the β-methylene signals was observed at -90°, the coalescence temperature was still not reached at -110°. From this information an upper limit of the rotational barriers around the central methylene carbons of 7.9 kcal could be calculated. © 1979.

引用

页码：1911 / 1915

页数：5

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