SEQUENCE OF A NOVEL CARBONIC ANHYDRASE-RELATED POLYPEPTIDE AND ITS EXCLUSIVE PRESENCE IN PURKINJE-CELLS

被引：72

作者：

KATO, K

机构：

[1] MRC Molecular Genetics Unit, Cambridge

来源：

FEBS LETTERS | 1990年 / 271卷 / 1-2期

关键词：

Carbonic anhydrase; cDNA cloning; Purkinje cell;

D O I：

10.1016/0014-5793(90)80390-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

I isolated a mouse cDNA clone encoding a novel polypeptide which has strong homology with carbonic anhydrase. Unlike the other carbonic anhydrases, it has an additional N-terminal domain with a glutamic acid stretch and an arginine substitutes one of the three histidine residues which bind zinc ion. In the central nervous system, carbonic anhydrase is known to be expressed only in glia cells, but this gene is expressed in neuron, but only in Purkinje cells. © 1990.

引用

页码：137 / 140

页数：4

共 13 条

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