INTRAMOLECULAR CLAISEN-TYPE CONDENSATIONS OF BETA-ACETOXY AMIDES OR IMIDES

被引：15

作者：

BRANDANGE, S

LEIJONMARCK, H

机构：

[1] Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)79590-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular Claisen-type condensation of amide 1 or amide 7 leads to the same delta-lactone in racemic (2) or enantiomerically pure form (4) respectively. A side-reaction producing the 11-membered ring compound 6 makes imide 3 unsuitable as a starting material for the synthesis of 4. A clean two-step reduction of 4 to 9 is also described.

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页码：3025 / 3028

页数：4

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