MOLECULAR AND CELLULAR BASIS OF CANCER INVASION AND METASTASIS - IMPLICATIONS FOR TREATMENT

被引：127

作者：

JIANG, WG

PUNTIS, MCA

HALLETT, MB

机构：

[1] Department of Surgery, University of Wales College of Medicine, Cardiff, CF44XN, Heath Park

来源：

BRITISH JOURNAL OF SURGERY | 1994年 / 81卷 / 11期

关键词：

D O I：

10.1002/bjs.1800811107

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In the past decade significant advances in establishing the underlying biological mechanisms of tumour invasion and metastasis have been made. Some of the triggering factors and genes relevant to metastatic spread have been identified. Advances have also been made in understanding the signal transduction pathways involved in invasion and metastasis. This increased comprehension of the malignant metastatic process has enabled new antimetastatic strategies to be devised. This review summarizes progress in these areas and discusses the implications for the treatment of metastasis.

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页码：1576 / 1590

页数：15

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