THE ROLE OF ADJUVANT SURGERY IN THE COMBINED MODALITY THERAPY OF SMALL-CELL BRONCHOGENIC-CARCINOMA AFTER A CHEMOTHERAPY-INDUCED PARTIAL REMISSION

被引：19

作者：

HOLOYE, PY ^{[1
]}

MCMURTREY, MJ ^{[1
]}

MOUNTAIN, CF ^{[1
]}

MURPHY, WK ^{[1
]}

DHINGRA, HM ^{[1
]}

UMSAWASDI, T ^{[1
]}

GLISSON, BS ^{[1
]}

LEE, JS ^{[1
]}

CARR, DT ^{[1
]}

VALDIVIESO, M ^{[1
]}

HONG, WK ^{[1
]}

机构：

[1] UNIV TEXAS,MD ANDERSON HOSP & TUMOR INST,CTR CANC,DEPT THORAC SURG,HOUSTON,TX 77030

来源：

JOURNAL OF CLINICAL ONCOLOGY | 1990年 / 8卷 / 03期

关键词：

D O I：

10.1200/JCO.1990.8.3.416

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twenty-six patients with a limited-disease presentation of small-cell bronchogenic carcinoma (SCBC) had surgery after achieving a partial remission with three cycles of chemotherapy. Persistent SCBC was found in 15 patients (58%), non-small-cell bronchogenic carcinoma (NSCBC) in six patients (23%), and no malignancy in five patients (19%). Twelve patients have died since surgery. Tumor-node-metastasis (TNM) staging prior to or after chemotherapy was not predictive of outcome, but an N0 status found at pathological examination of the surgical specimen was predictive of long-term survival. Median survival for this group of patients was 25 months. Adjuvant surgery is feasible and may be beneficial.

引用

页码：416 / 422

页数：7

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