FRAGMENTATION OF STEREOISOMERIC ANDROSTANEDIOL TERT-BUTYLDIMETHYLSILYL ETHERS - STUDY BY LINKED FIELD SCANNING

被引：18

作者：

GASKELL, SJ ^{[1
]}

PIKE, AW ^{[1
]}

MILLINGTON, DS ^{[1
]}

机构：

[1] VG ORGAN LTD,ALTRINCHAM WA14 5RZ,CHESHIRE,ENGLAND

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 02期

关键词：

D O I：

10.1002/bms.1200060208

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The major fragmentation pathways of eight isomeric androstane‐3,17‐diols, as their bis‐t‐butyldimethylsilyl ethers, were elucidated by linked scanning of the magnetic and electric fields in a double focusing mass spectrometer. Four competing pathways were observed, each characterized by losses of alkylsilanol moieties from a common [M–C4H9]+ precursor. Pronounced differences in the spectra obtained by linked scans complement the coventional mas spectra in the differentiation of the isomeric structures. Copyright © 1979 Heyden & Son Ltd

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页码：78 / 81

页数：4

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