DESMIN AS AN IMMUNOCHEMICAL MARKER OF HUMAN DECIDUAL CELLS AND ITS EXPRESSION IN MENSTRUAL FLUID

被引：14

作者：

HALPERIN, R ^{[1
]}

FLEMINGER, G ^{[1
]}

KRAICER, PF ^{[1
]}

HADAS, E ^{[1
]}

机构：

[1] TEL AVIV UNIV,GEORGE S WISE FAC LIFE SCI,DEPT BIOTECHNOL,IL-69978 TEL AVIV,ISRAEL

来源：

HUMAN REPRODUCTION | 1991年 / 6卷 / 02期

关键词：

DECIDUA; DESMIN; INTERMEDIATE FILAMENT; MONOCLONAL ANTIBODY;

D O I：

10.1093/oxfordjournals.humrep.a137302

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The expression of intermediate filament proteins in human endometrial tissue was examined. Desmin was selectively expressed in decidualized stroma, as demonstrated by SDS-PAGE analysis and positive response with a monoclonal antibody specific for desmin in ELISA and in western blot analysis. The same monoclonal antibody specifically stained human decidual cells in decidualized endometrium (secretory endometrium) in formalin-fixed paraffin-embedded sections prepared from diagnostic curettage samples. Desmin was also detected in menstrual fluid. Therefore, desmin might serve as a biochemical and histochemical marker of human decidualized endometrium.

引用

页码：186 / 189

页数：4

共 13 条

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