REACTIVITY AND REACTIONS OF AROMATIC ACETYLENIC ACIDS AND KETONES

被引：7

作者：

DREWES, SE

DOUGLASS, D

MALISSAR, DGS

ROOS, GHP

KAYE, PT

机构：

[1] Chemistry Department, University of Natal, Pietermaritzburg 3200

[2] Department of Chemistry, Rhodes University, Grahamstown

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 06期

关键词：

D O I：

10.1039/p19900001507

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Some novel reactions of the acetylenic carboxylic acid, 4-oxo-6-phenylhexynoic acid with succinic anhydride are described. One of the products of the reaction is a butyrolactone derivative. Transformation of 4-phenylbut-3-yn-2-one results in the formation of α,β-acetylenic-α′-alkoxy epoxides which are of interest as anti-tumour compounds.

引用

页码：1507 / 1511

页数：5

共 18 条

[1] [Anonymous], 1973, NATURALLY OCCURRING
[2] AROSIO R, 1983, THESIS U MILANO
[3] BURKE SD, 1987, TETRAHEDRON LETT, V28, P3095
[4] CHEREST M, 1968, TETRAHEDRON LETT, P2201
[5] DIMETHYLSULFOXONIUM METHYLIDE
COREY, EJ
CHAYKOVSKY, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1962, 84 (05) : 867 - &
[6] ISOLATION OF HYPOXOSIDE FROM HYPOXIS ROOPERI AND SYNTHESIS OF (E)-1,5-BIS(3',4'-DIMETHOXYPHENYL)PENT-4-EN-1-YNE
DREWES, SE
HALL, AJ
LEARMONTH, RA
UPFOLD, UJ
[J]. PHYTOCHEMISTRY, 1984, 23 (06) : 1313 - 1316
[7] DREWES SE, 1983, Patent No. 92226
[8] DREWES SE, 1985, Patent No. 130829
[9] The synthesis of acetylenic ketones from acetylenic Grignard reagents
Kroeger, JW
Nieuwland, JA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1936, 58 : 1861 - 1863
[10] RESEARCH ON AFRICAN MEDICINAL-PLANTS .2. HYPOXOSIDE, A NEW GLYCOSIDE OF UNCOMMON STRUCTURE FROM HYPOXIS-OBTUSA BUSCH
BETTOLO, GBM
PATAMIA, M
NICOLETTI, M
GALEFFI, C
MESSANA, I
[J]. TETRAHEDRON, 1982, 38 (11) : 1683 - 1687

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