ALPHA-HALOENONES FROM SECONDARY ALKYNOLS

被引：30

作者：

ANGARA, GJ ^{[1
]}

MCNELIS, E ^{[1
]}

机构：

[1] NYU,DEPT CHEM,NEW YORK,NY 10003

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)71246-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Iodoenones and alpha-bromoenones are formed from secondary alkynols by the use of the appropriate N-halosuccinimide and a catalytic amount of certain Lewis acids. For example, 3-hexyn-2-ol (1) was converted to (Z)-4-iodo-4-hexen-3-one (2) in 85-95% yields with an equimolar quantity of NIS and tenth molar (hydroxy (toxyloxy) iodo) benzene (3) in methanol or 1-methyl-2-pyrrolididone.

引用

页码：2099 / 2100

页数：2

共 11 条

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