RAT-LIVER PARAOXONASE - SUBCELLULAR-DISTRIBUTION AND CHARACTERIZATION

被引：32

作者：

GIL, F

PLA, A

GONZALVO, MC

HERNANDEZ, AF

VILLANUEVA, E

机构：

[1] UNIV HOSP GRANADA,FAC MED,DEPT LEGAL MED,AVDA MADRID 11,E-18071 GRANADA,SPAIN

[2] UNIV HOSP GRANADA,FAC MED,TOXICOL SERV,E-18071 GRANADA,SPAIN

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1993年 / 87卷 / 1-3期

关键词：

ORGANOPHOSPHATES; A-ESTERASE; PARAOXONASE; RAT; LIVER;

D O I：

10.1016/0009-2797(93)90036-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The subcellular localization and some biochemical properties of rat liver paraoxonase have been studied in order to establish a correlation with plasma enzyme. The whole paraoxonase activity was found in the microsomal fraction. Rat plasma and liver paraoxonase showed similar optimum pH (8.5), K(m) (0.4 mM) and calcium requirement, but differed in the response to several inhibitors.

引用

页码：149 / 154

页数：6

共 21 条

[1] SERUM ESTERASES .1. 2 TYPES OF ESTERASE (A AND B) HYDROLYSING PARA-NITROPHENYL ACETATE, PROPIONATE AND BUTYRATE, AND A METHOD FOR THEIR DETERMINATION [J].