IMPROVED PERFORMANCE OF CARBON-PASTE AMPEROMETRIC BIOSENSORS THROUGH THE INCORPORATION OF FUMED SILICA

被引：47

作者：

WANG, J

NASER, N

机构：

[1] Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico

来源：

ELECTROANALYSIS | 1994年 / 6卷 / 07期

关键词：

FUMED SILICA; CARBON PASTE; BIOSENSOR; ENZYME ELECTRODES;

D O I：

10.1002/elan.1140060707

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The sensitivity and stability of carbon paste enzyme electrodes are greatly enhanced through the incorporation of fumed silica within the paste matrix. The improved performance is attributed to the adsorptive and electrocatalytic properties of the silica nanoparticles. The electrocatalytic action results in a substantial lowering of the overvoltage for both the oxidation and reduction of the enzymatically liberated peroxide species. Highly selective, low-potential, biosensing of glucose is thus accomplished in the presence of coexisting acetaminophen, ascorbic acid, or uric acid. The enhanced performance accrued from the presence of silica is also illustrated for mediator (dimethyl ferrocene)-containing pastes. High enzymatic activity is maintained over prolonged periods. The silica modification strategy provides an effective, fast, and inexpensive route for immobilizing enzymes within carbon paste matrices.

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页码：571 / 575

页数：5

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