PRIMIDONE AND PHENOBARBITAL DURING LACTATION PERIOD IN EPILEPTIC WOMEN - TOTAL AND FREE DRUG SERUM LEVELS IN THE NURSED INFANTS AND THEIR EFFECTS ON NEONATAL BEHAVIOR

被引：52

作者：

KUHNZ, W

KOCH, S

HELGE, H

NAU, H

机构：

[1] FREE UNIV BERLIN,INST TOXIKOL & EMBRYONALPHARMAKOL,GARYSTR 5,D-1000 BERLIN 33,FED REP GER

[2] FREE UNIV BERLIN,KINDERKLIN,D-1000 BERLIN 33,FED REP GER

来源：

DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS | 1988年 / 11卷 / 03期

关键词：

D O I：

10.1159/000457682

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：147 / 154

页数：8

共 12 条

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[3]

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HUTH, H ;

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HELGE, H .

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 1983, 108 (07) :250-257

[5] AUTOMATED HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC ASSAY FOR ANTIEPILEPTIC DRUGS AND THEIR MAJOR METABOLITES BY DIRECT INJECTION OF SERUM SAMPLES [J].

KUHNZ, W ;

NAU, H .

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[6]

MORSELLI PL, 1977, DRUG DISPOSITION DEV, P311

[7] ANTI-CONVULSANTS DURING PREGNANCY AND LACTATION - TRANS-PLACENTAL, MATERNAL AND NEONATAL PHARMACOKINETICS [J].

NAU, H ;

KUHNZ, W ;

EGGER, HJ ;

RATING, D ;

HELGE, H .

CLINICAL PHARMACOKINETICS, 1982, 7 (06) :508-543

[8] PLACENTAL-TRANSFER AND PHARMACOKINETICS OF PRIMIDONE AND ITS METABOLITES PHENOBARBITAL, PEMA AND HYDROXYPHENOBARBITAL IN NEONATES AND INFANTS OF EPILEPTIC MOTHERS [J].

NAU, H ;

RATING, D ;

HAUSER, I ;

JAGER, E ;

KOCH, S ;

HELGE, H .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 18 (01) :31-42

[9]

NAU H, 1982, EPILEPSY PREGNANCY C, P121

[10]

SCHOTTELIUS DD, 1982, ANTIEPILEPTIC DRUGS, P405

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