USE OF NATIVE AND CHEMICALLY MODIFIED CYCLODEXTRINS FOR THE CAPILLARY ELECTROPHORETIC SEPARATION OF ENANTIOMERS

被引：113

作者：

SEPANIAK, MJ

COLE, RO

CLARK, BK

机构：

[1] Department of Chemistry, The University of Tennessee, Knoxville

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1992年 / 15卷 / 6-7期

基金：

美国能源部;

关键词：

D O I：

10.1080/10826079208018848

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Capillary zone electrophoresis is shown to be useful for the separation of select enantiomers via the use of mobile phases containing cyclodextrins (CDs). Both native and chemically modified CDs are utilized herein. Parameters important in achieving enantiomeric separations are CD type, concentration, and mobile phase pH. In addition, rapid (1 minute) enantiomeric separations are demonstrated. Experimental parameters important in attaining short analysis times are discussed.

引用

页码：1023 / 1040

页数：18

共 22 条

[1] ALLENMARK SG, E HORWOOD SERIES ANA, V146
[2] ARMSTRONG DW, 1991, LC GC-MAG SEP SCI, V9, P646
[3] ARMSTRONG DW, 1988, CRIT REV ANAL CHEM, V19, P175
[4] ARMSTRONG DW, CHROMATOGRAPHIC CHIR, V40, P131
[5] BOCEK P, 1989, J MICROCOLUMN SEP, V1, P190
[6] COLE RO, 1990, HRC-J HIGH RES CHROM, V13, P579
[7] DISTRIBUTION AND ENANTIOMERIC COMPOSITION OF AMINO-ACIDS IN THE MURCHISON METEORITE
ENGEL, MH
NAGY, B
[J]. NATURE, 1982, 296 (5860) : 837 - 840
[8] USE OF CYCLODEXTRINS IN CAPILLARY ZONE ELECTROPHORESIS - RESOLUTION OF TERBUTALINE AND PROPRANOLOL ENANTIOMERS
FANALI, S
[J]. JOURNAL OF CHROMATOGRAPHY, 1991, 545 (02): : 437 - 444
[9] EFFECT OF ADDITION OF ORGANIC-SOLVENT ON THE SEPARATION OF POSITIONAL ISOMERS IN HIGH-VOLTAGE CAPILLARY ZONE ELECTROPHORESIS
FUJIWARA, S
HONDA, S
[J]. ANALYTICAL CHEMISTRY, 1987, 59 (03) : 487 - 490
[10] EFFECT OF TEMPERATURE-GRADIENTS ON THE EFFICIENCY OF CAPILLARY ZONE ELECTROPHORESIS SEPARATIONS
GRUSHKA, E
MCCORMICK, RM
KIRKLAND, JJ
[J]. ANALYTICAL CHEMISTRY, 1989, 61 (03) : 241 - 246

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