ACTIVITY OF COMPOUND-G2 ISOLATED FROM ALFALFA ROOTS IN EXPERIMENTAL DERMATOPHYTE INFECTION

被引:6
作者
EVRON, R
GUIZIE, M
ZEHAVI, U
POLACHECK, I
机构
[1] HEBREW UNIV JERUSALEM,HADASSAH MED CTR,DEPT CLIN MICROBIOL,POB 12000,IL-91120 JERUSALEM,ISRAEL
[2] HEBREW UNIV JERUSALEM,HADASSAH MED CTR,DEPT DERMATOL,IL-91120 JERUSALEM,ISRAEL
[3] HEBREW UNIV JERUSALEM,FAC AGR,DEPT BIOCHEM & HUMAN NUTR,IL-76100 REHOVOT,ISRAEL
关键词
D O I
10.1128/AAC.34.8.1600
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Compound G2 isolated from alfalfa roots was applied topically to skin lesions of guinea pigs experimentally infected with the dermatophyte Trichophyton mentagrophytes var. granulare. After 12 to 15 applications, 80% of the infected lesions were cured, as judged by clinical and microbial criteria, compared with 20% of the untreated lesions which healed spontaneously (P < 0.01).
引用
收藏
页码:1600 / 1601
页数:2
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