CITRATE ANTICOAGULATION DURING INVIVO SIMULATION OF SLOW HEMOFILTRATION

被引：13

作者：

AHMAD, S

YEO, KT

JENSEN, WM

DELLANDICHO

GREGORY, B

MORITZ, JL

KENNY, M

机构：

[1] Department of Medicine, University of Washington, Seattle, WA

[2] Department of Laboratory Medicine, University of Washington, Seattle, WA

来源：

BLOOD PURIFICATION | 1990年 / 8卷 / 04期

关键词：

Anticoagulation; Bleeding; Citrate; Hemofiltration; Heparin; Sodium citrate;

D O I：

10.1159/000169964

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Citrate anticoagulation has been used as an alternative to heparin for hemodialysis in high-risk patients; however, its use in hemofiltration has not been well studied. We examined citrate in 6 patients placed on slow hemofiltration for up to 6 h duration. During the experiments, the systemic citrate level increased from a baseline average of 0.15 to 0.55 mmol/1, and then decreased to0.27 mmol/1. The citrate was freely filtered. The systemic total and ionized calcium decreased very slightly and no untoward effects were noted. Anticoagulation was successful. This preliminary study suggests that citrate anticoagulation can be used in slow hemofiltration. © 1990 S. Karger AG, Basel.

引用

页码：177 / 182

页数：6

共 15 条

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