VESICA - COMPUTER-GRAPHICS MODELING OF LIPID VESICLES

被引：4

作者：

LAWRENCE, SM

LAWRENCE, MJ

BARLOW, DJ

机构：

[1] UNIV LONDON,KINGS COLL,DEPT PHARM,MANRESA RD,LONDON SW3 6LX,ENGLAND

[2] UNIV LONDON,KINGS COLL,DEPT PHARMACOL,LONDON SW3 6LX,ENGLAND

来源：

JOURNAL OF MOLECULAR GRAPHICS | 1991年 / 9卷 / 04期

关键词：

PHOSPHOLIPID VESICLES; ICOSAHEDRAL TESSELLATION; DRUG DELIVERY; LIPID BILAYER; MEMBRANES;

D O I：

10.1016/0263-7855(91)80014-Q

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A vesicle simulation and computer analysis program, VESICA, is described which employs spherical projections of triangularly tessellated icosahedra to produce molecular graphics models of the three-dimensional structures of lipid vesicles. The program is used to analyze the molecular architecture of small unilamellar vesicles of dipalmitoyl-phosphatidylcholine and is demonstrated as a worthwhile investigative tool for determining the factors that govern the minimum vesicle size.

引用

页码：218 / &

共 20 条

[1]

BANGHAM AD, 1974, METHODS MEMBRANE BIO, V1, P1

[2]

BARRET AN, 1987, SPATIAL STRUCTURE MI, P343

[3] MINIMAL SIZE PHOSPHATIDYLCHOLINE VESICLES - EFFECTS OF RADIUS OF CURVATURE ON HEAD GROUP PACKING AND CONFORMATION [J].