SERUM PROSTATIC ACID-PHOSPHATASE, GAMMA-SEMINOPROTEIN AND PROSTATIC SPECIFIC ANTIGEN IN HEMODIALYSIS-PATIENTS

被引:20
作者
SASAGAWA, I
NAKADA, T
HASHIMOTO, T
ISHIGOOKA, M
KUBOTA, Y
HIRANO, K
HIRANO, J
SUZUKI, Y
机构
[1] Department of Urology, Yamagata University, School of Medicine, Yamagata
关键词
PROSTATIC ACID PHOSPHATASE; GAMMA-SEMINOPROTEIN; PROSTATIC SPECIFIC ANTIGEN; HEMODIALYSIS;
D O I
10.1159/000282326
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Serum concentrations of prostatic acid phosphatase (PAP), gamma-seminoprotein (gamma-Sm) and prostatic specific antigen (PSA) were measured in 31 hemodialysis patients without clinical signs of malignant disease. PAP, gamma-Sm and PSA levels in serum were not significantly different between control and hemodialysis groups. A significant reduction in these tumor markers was not found after dialysis treatment. This indicates that the measurement of PAP, gamma-Sm and PSA in serum is useful for the detection of prostatic cancer in patients undergoing hemodialysis.
引用
收藏
页码:181 / 183
页数:3
相关论文
共 16 条
[1]  
Arai Y., Yoshiki T., Okada T., Et al., Multiple marker evaluation in prostatic cancer using prostatic specific antigen, gamma-scminoprotein and prostatic acid phosphatases, Urol Int, 44, pp. 135-140, (1989)
[2]  
Kaplan J., Prestidgc B.R., Cox R.S., Et al., Prostatic specific antigen after irradiation for prostatic carcinoma, J Urol, 144, pp. 1172-1176, (1990)
[3]  
Filella X., Cases A., Moline R., Et al., Tumor markers in patients with chronic renal failure, Int J Biol Markers, 5, pp. 85-88, (1990)
[4]  
Kabalin J.N., Hornberger J.C., Prostatic specific antigen is not excreted by human kidney or eliminated by routine hemodialysis, Urology, 37, pp. 308-310, (1991)
[5]  
Matas A.J., Simmonds R.L., Kjellstrand C.M., Et al., Increased incidence of malignancy during chronic renal failure, Lancet, 1, pp. 883-885, (1975)
[6]  
Sasagawa I., Suzuki K., Ishizaki M., Et al., Prostatic cancer in a patient on long-term hemodialysis, Nephron, 59, pp. 506-507, (1991)
[7]  
Dunnill M.S., Millard P.R., Oliver D., Acquired eystic disease of the kidneys. A hazard of long-term intermittent maintenance hemodialysis, J Clin Pathol, 30, pp. 868-877, (1977)
[8]  
Goldblum S.E., Reed W.P., Host defenses and immunologic alterations associated with chronic hemodialysis, Ann Intern Med, 93, pp. 597-613, (1980)
[9]  
Curtis J.R., Cancer and patients with end-stage renal failure, Br Med J, 284, pp. 69-70, (1982)
[10]  
Lurie B.B., Loewenstein M.S., Zameheck N., Elevated circulating CEA levels in benign exlrahe-patic biliary tract obstruction and inflammation, JAMA, 233, pp. 326-330, (1975)