BOUND WATER IN THE COLLAGEN-LIKE TRIPLE-HELICAL STRUCTURE

被引：67

作者：

LAZAREV, YA ^{[1
]}

GRISHKOVSKY, BA ^{[1
]}

KHROMOVA, TB ^{[1
]}

LAZAREVA, AV ^{[1
]}

GRECHISHKO, VS ^{[1
]}

机构：

[1] ACAD SCI USSR,INST PROT RES,PUSHCHINO 142292,USSR

来源：

BIOPOLYMERS | 1992年 / 32卷 / 02期

关键词：

D O I：

10.1002/bip.360320209

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ir amide bands of the triple-helical polytripeptides and collagens upon hydration of films are investigated. On the basis of our assignment of the amide I components, the formation of hydrogen bonds between the peptide backbone and structural water is studied. The C1O1 - HOH hydrogen bonds are found more ordered than the C3O3 - HOH hydrogen bonds. The specific incorporation of water in the triple helix is followed by multistep conformational changes and by increasing of the interpeptide hydrogen-bond strength. The formation of the polypeptide hydrate structure depending on the amino acid composition and the chain length is examined.

引用

页码：189 / 195

页数：7

共 26 条

[1] THERMAL-PROPERTIES OF COLLAGEN IN HELICAL AND RANDOM COILED STATES IN TEMPERATURE-RANGE FROM 4DEGREES TO 300DEGREESK [J].