SYNTHESIS AND BIOLOGICAL PROPERTIES OF ALPHA-MONOMETHYL AND ALPHA-DIFLUOROMETHYL DERIVATIVES OF TRYPTOPHAN AND 5-HYDROXYTRYPTOPHAN

被引：75

作者：

SCHIRLIN, D ^{[1
]}

GERHART, F ^{[1
]}

HORNSPERGER, JM ^{[1
]}

HAMON, M ^{[1
]}

WAGNER, J ^{[1
]}

JUNG, MJ ^{[1
]}

机构：

[1] FAC MED PITIE SALPETRIERE,F-75634 PARIS 13,FRANCE

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 01期

关键词：

D O I：

10.1021/jm00396a007

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：30 / 36

页数：7

共 26 条

[1] DIRECT SYNTHESIS OF ALPHA-HALOGENOMETHYL-ALPHA-AMINO ACIDS FROM THE PARENT ALPHA-AMINO-ACIDS [J].

BEY, P ;

VEVERT, JP ;

VANDORSSELAER, V ;

KOLB, M .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (15) :2732-2742

[2] PROPOSALS FOR THE CLASSIFICATION AND NOMENCLATURE OF FUNCTIONAL RECEPTORS FOR 5-HYDROXYTRYPTAMINE [J].

BRADLEY, PB ;

ENGEL, G ;

FENIUK, W ;

FOZARD, JR ;

HUMPHREY, PPA ;

MIDDLEMISS, DN ;

MYLECHARANE, EJ ;

RICHARDSON, BP ;

SAXENA, PR .

NEUROPHARMACOLOGY, 1986, 25 (06) :563-576

[3] ALPHA-MONOFLUOROMETHYL AND ALPHA-DIFLUOROMETHYL PUTRESCINE AS ORNITHINE DECARBOXYLASE INHIBITORS - INVITRO AND INVIVO BIOCHEMICAL-PROPERTIES [J].

DANZIN, C ;

BEY, P ;

SCHIRLIN, D ;

CLAVERIE, N .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (23) :3871-3878

[4] ALPHA-METHYLTRYPTOPHAN - EFFECTS ON CEREBRAL MONOOXYGENASES INVITRO AND INVIVO [J].

GAL, EM ;

CHRISTIANSEN, PA .

JOURNAL OF NEUROCHEMISTRY, 1975, 24 (01) :89-95

[5] INHIBITION OF HISTAMINE SYNTHESIS IN BRAIN BY ALPHA-FLUOROMETHYLHISTIDINE, A NEW IRREVERSIBLE INHIBITOR - INVITRO AND INVIVO STUDIES [J].

GARBARG, M ;

BARBIN, G ;

RODERGAS, E ;

SCHWARTZ, JC .

JOURNAL OF NEUROCHEMISTRY, 1980, 35 (05) :1045-1052

[6]

GERHART F, UNPUB

[7] RAT-BRAIN STEM TRYPTOPHAN-HYDROXYLASE - MECHANISM OF ACTIVATION BY CALCIUM [J].

HAMON, M ;

BOURGOIN, S ;

ARTAUD, F ;

HERY, F .

JOURNAL OF NEUROCHEMISTRY, 1977, 28 (04) :811-818

[8]

HAMON M, 1978, MOL PHARMACOL, V14, P99

[9]

HORNSPERGER JM, 1984, THESIS U L PASTEUR S

[10] INHIBITION OF MONO-AMINE SYNTHESIS BY IRREVERSIBLE BLOCKADE OF AROMATIC AMINO-ACID DECARBOXYLASE WITH ALPHA-MONOFLUOROMETHYLDOPA [J].

JUNG, MJ ;

PALFREYMAN, MG ;

WAGNER, J ;

BEY, P ;

RIBEREAUGAYON, G ;

ZRAIKA, M ;

KOCHWESER, J .

LIFE SCIENCES, 1979, 24 (11) :1037-1042

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