GENETIC STUDY OF CYSTIC FIBROSIS OF PANCREAS USING WHITE BLOOD CELL CULTURES

被引：22

作者：

DANES, BS

FOLEY, KM

DILLON, SD

BEARN, AG

机构：

[1] Division of Human Genetics, Department of Medicine, Cornell University Medical College

来源：

NATURE | 1969年 / 222卷 / 5194期

关键词：

D O I：

10.1038/222685a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

CYSTIC fibrosis of the pancreas is probably the most frequent inherited disease in Caucasian populations. The use of antibiotics and improved medical management has increased the importance of this highly lethal genetic disorder. Formal genetic analysis indicates that the disease is inherited in a simple autosomal recessive fashion; the frequency of the clinically unaffected heterozygous carriers has been estimated to be approximately one in twenty-five live births1. © 1969 Nature Publishing Group.

引用

页码：685 / &

共 12 条

[1]

CHILDS B, 1956, 18 ROSS PED RES C FI, P87

[2]

CROW JE, 1965, PHS1163 US DEP HEALT

[3]

DANES BS, 1968, LANCET, V1, P1061

[4] HURLERS SYNDROME - EFFECT OF RETINOL (VITAMIN A ALCOHOL) ON CELLULAR MUCOPOLYSACCHARIDES IN CULTURED HUMAN SKIN FIBROBLASTS [J].