ECONOMIC COMPARISON OF CALCIUM FUMARATE AND SODIUM FUMARATE PRODUCTION BY RHIZOPUS-ARRHIZUS

被引：40

作者：

GANGL, IC ^{[1
]}

WEIGAND, WA ^{[1
]}

KELLER, FA ^{[1
]}

机构：

[1] CAMBRIDGE BIOSCI CORP,WORCESTER,MA 01605

来源：

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | 1990年 / 24-5卷

关键词：

calcium carbonate; economic analysis; fermentation; Fumaric acid; sodium carbonate;

D O I：

10.1007/BF02920287

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The economics of using Na2CO3 rather than CaCO3 as the neutralizing agent in fumaric acid production by Rhizopus arrhizus is investigated and compared with the benzene route. Because sodium fumarate, unlike calcium fumarate, is soluble, downstream processing is simplified by requiring less equipment and no heat, and also allows the reuse of cells. In spite of a fumaric acid productivity (g/L/h) 2.4 x lower than the CaCO3 case, the Na2CO3 alternative with cell reuse has a higher rate of return. However, with the current cost of petroleum, the selling price of fumaric acid from the benzene route is half as much as from an idealized Na2CO3 fermentation. © 1990 Humana Press Inc.

引用

页码：663 / 677

页数：15

共 24 条

[1]

BAILEY JE, 1986, BIOCH ENG FUNDAMENTA, P802

[2]

Barker R. S., 1966, Patent No. [US 3262972 A, 3262972]

[3]

BARTHOLOMEW WH, 1979, MICROBIAL TECHNOLOGY, V2, P463

[4]

BOUCHARD EF, 1981, KIRKOTHMER ENCY CHEM, V6, P150

[5]

BUSCHE RM, 1986, BIOTECH BIOENG S, V17, P565

[6]

DALE GH, 1981, KIRKOTHMER ENCY CHEM, V12, P870

[7]

FAUST U., 1987, FUNDAMENTALS BIOTECH, P601

[8]

FERBER KH, 1981, KIRKOTHMER ENCY CHEM, V3, P744

[9]

FOSTER JW, 1949, BACTERIOL REV, V11, P167

[10] IMPROVED RATE OF FUMARIC-ACID PRODUCTION BY TWEENS AND VEGETABLE-OILS IN RHIZOPUS ARRHIZUS [J].

GOLDBERG, I ;

STIEGLITZ, B .

BIOTECHNOLOGY AND BIOENGINEERING, 1985, 27 (07) :1067-1069

← 1 2 3 →