ALFENTANIL FOR URGENT CESAREAN-SECTION IN A PATIENT WITH SEVERE MITRAL-STENOSIS AND PULMONARY-HYPERTENSION

We present the case of a parturient with severe mitral stenosis and pulmonary hypertension who received general anaesthesia using alfentanil for urgent Caesarean section. Alfentanil promoted haemodynamic stability and allowed immediate postoperative extubation. Epidural morphine provided postoperative analgesia. This combination permitted early ambulation and prevention of thromboembolism. A disadvantage of this technique, neontal respiratory depression, was promptly reversed with a single dose ofnaloxone. The anaesthetic management of mitral stenosis in pregnancy is discussed and the neonatal pharmacokinetics of maternally administered alfentanil are presented. © 1990 Canadian Anesthesiologists.