SINGLE-BLIND STUDY OF DYSTROPHIN STAINING IN CARRIERS OF DUCHENNE MUSCULAR-DYSTROPHY

被引：6

作者：

BERNIER, FP

GREENBERG, CR

HALLIDAY, WC

WROGEMANN, K

机构：

[1] UNIV MANITOBA,DEPT BIOCHEM & MOLEC BIOL,WINNIPEG R3E 0W3,MANITOBA,CANADA

[2] UNIV MANITOBA,DEPT PEDIAT & CHILD HLTH,WINNIPEG R3E 0W3,MANITOBA,CANADA

[3] UNIV MANITOBA,DEPT PATHOL,WINNIPEG R3E 0W3,MANITOBA,CANADA

[4] UNIV MANITOBA,DEPT HUMAN GENET,WINNIPEG R3E 0W3,MANITOBA,CANADA

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1993年 / 20卷 / 01期

关键词：

D O I：

10.1017/S0317167100047399

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A single-blind study of dystrophin staining in skeletal muscle was performed in 13 biopsies from carriers of Duchenne Muscular Dystrophy (DMD) and controls. The results indicate that immunohistochemical analysis of dystrophin staining is a valuable diagnostic test for DMD carriers when DNA for testing is unavailable from critical family members or is uninformative, when creatine kinase (CK) values are conflicting or when CK values must be used in isolation.

引用

页码：44 / 47

页数：4

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