FORMATION OF 2,2-DISUBSTITUTED 1,3-CYCLOPENTANEDIONES FROM KETALS WITH 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE

被引：21

作者：

WU, YJ ^{[1
]}

STRICKLAND, DW ^{[1
]}

JENKINS, TJ ^{[1
]}

LIU, PY ^{[1
]}

BURNELL, DJ ^{[1
]}

机构：

[1] MEM UNIV NEWFOUNDLAND,DEPT CHEM,ST JOHNS A1B 3X7,NEWFOUNDLAND,CANADA

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1993年 / 71卷 / 09期

关键词：

D O I：

10.1139/v93-169

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The direct formation of 2,2-disubstituted 1,3-cyclopentanedione compounds by a Lewis acid catalysed reaction with 1,2-bis(trimethylsilyloxy)cyclobutene proceeds in good to excellent yields with unhindered ketals, but steric hindrance yields considerably. A carbonyl group alpha or beta to the ketal, or a carbon-carbon double bond alpha to the ketal, action completely. Orthoesters do not give geminally acylated products in synthetically useful yields.

引用

页码：1311 / 1318

页数：8

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