AN EFFICIENT SYNTHESIS OF 3-VINYLPYRROLES BY STILLE COUPLING REACTION OF 3-IODOPYRROLES WITH VINYLTRIBUTYLTIN

被引：16

作者：

WANG, JJ ^{[1
]}

SCOTT, AI ^{[1
]}

机构：

[1] TEXAS A&M UNIV,DEPT CHEM,CTR BIOL NMR,COLLEGE STN,TX 77843

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 39期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0040-4039(95)01459-U

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several 3-vinylpyrrolic compounds with different functional groups have been synthesized by Stille coupling reaction of S-iodopyrroles with vinyltributyltin in 80-92% yields. Under the same reaction conditions it was found that 3-bromopyrroles gave the corresponding product in very poor yield, while 3-chloropyrroles were unreactive.

引用

页码：7043 / 7046

页数：4

共 6 条

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[2] FARNIER M, 1973, B SOC CHIM FR, P351
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MORRIS, IK
SNOW, KM
SMITH, KM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (23) : 5567 - 5574
[5] MITCHELL TN, 1992, SYNTHESIS-STUTTGART, P803
[6] THE PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS OF ORGANOTIN REAGENTS WITH ORGANIC ELECTROPHILES
STILLE, JK
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1986, 25 (06): : 508 - 523

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