ADJUVANT HIGH-DOSE INTRAVENOUS GAMMA-GLOBULIN IN THE TREATMENT OF PEMPHIGUS AND BULLOUS PEMPHIGOID - EXPERIENCE IN 6 PATIENTS

被引：84

作者：

BECKERS, RCY ^{[1
]}

BRAND, A ^{[1
]}

VERMEER, BJ ^{[1
]}

BOOM, BW ^{[1
]}

机构：

[1] LEIDEN UNIV HOSP,DEPT IMMUNOL,2300 RC LEIDEN,NETHERLANDS

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1995年 / 133卷 / 02期

关键词：

D O I：

10.1111/j.1365-2133.1995.tb02631.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

At present, initial high-dose prednisone is the treatment of choice for patients with pemphigus and bullous pemphigoid. To reduce the risks associated with long-term corticosteroid treatment, other immunosuppressants are often given as steroid-sparing agents. Occasionally, the dose of steroids cannot be reduced. In this study, we report six patients with pemphigus vulgaris, pemphigus foliaceus and bullous pemphigoid, in whom the daily corticosteroid dose could only be tapered to acceptable, effective, maintenance levels following treatment with high-dose intravenous gammaglobulin.

引用

页码：289 / 293

页数：5

共 14 条

[1] TREATMENT OF 9 CASES OF PEMPHIGUS VULGARIS WITH CYCLOSPORINE [J].

BARTHELEMY, H ;

FRAPPAZ, A ;

CAMBAZARD, F ;

MAUDUIT, G ;

ROUCHOUSE, B ;

KANITAKIS, J ;

SOUTEYRAND, P ;

CLAUDY, AL ;

THIVOLET, J .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1988, 18 (06) :1262-1266

[2]

Baruah D R, 1984, Br J Sports Med, V18, P128

[3]

DWYER JM, 1992, NEW ENGL J MED, V326, P107

[4] BULLOUS PEMPHIGOID AND INTRAVENOUS GAMMA-GLOBULIN [J].

GODARD, W ;

ROUJEAU, JC ;

GUILLOT, B ;

ANDRE, C ;

RIFLE, G .

ANNALS OF INTERNAL MEDICINE, 1985, 103 (06) :965-965

[5] EFFECTS OF INTRAVENOUS GAMMA-GLOBULIN IN PEMPHIGUS [J].

HUMBERT, P ;

DERANCOURT, C ;

AUBIN, F ;

AGACHE, P .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1990, 22 (02) :326-326

[6]

IMBACH P, 1981, LANCET, V1, P1228

[7] MANAGEMENT OF PEMPHIGUS WITH GOLD COMPOUNDS - LONG-TERM FOLLOW-UP REPORT [J].

PENNEYS, NS ;

EAGLSTEIN, WH ;

FROST, P .

ARCHIVES OF DERMATOLOGY, 1976, 112 (02) :185-187

[8]

POLLACK S, 1982, NEW ENGL J MED, V307, P253

[9] PEMPHIGUS VULGARIS - RESULTS OF TREATMENT WITH GOLD AS A STEROID-SPARING AGENT IN A SERIES OF 13 PATIENTS [J].

POULIN, Y ;

PERRY, HO ;

MULLER, SA .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1984, 11 (05) :851-857

[10] PLASMA-EXCHANGE IN PEMPHIGUS - UNCONTROLLED STUDY OF 10 PATIENTS [J].

ROUJEAU, JC ;

ANDRE, C ;

FABRE, MJ ;

LAURET, P ;

FLECHET, ML ;

KALIS, B ;

REVUZ, J ;

TOURAINE, R .

ARCHIVES OF DERMATOLOGY, 1983, 119 (03) :215-221

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