GENETIC-VARIATION IN ALKALINE-PHOSPHATASE OF THE HOUSE MOUSE (MUS-MUSCULUS) WITH EMPHASIS ON A MANGANESE-REQUIRING ISOENZYME

被引：43

作者：

WILCOX, FH

HIRSCHHORN, L

TAYLOR, BA

WOMACK, JE

RODERICK, TH

机构：

[1] JACKSON LAB, BAR HARBOR, ME 04609 USA

[2] TEXAS A&M UNIV, INST COMPARAT MED, DEPT VET PATHOL, COLLEGE STN, TX 77843 USA

来源：

BIOCHEMICAL GENETICS | 1979年 / 17卷 / 11-1期

关键词：

alkaline phosphatase; blood plasma; intestine; kidney; liver; Mus musculus;

D O I：

10.1007/BF00504347

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genetic variation among inbred strains is described for electrophoretic migration of alkaline phosphatase from intestine, kidney, blood plasma, and three isozymes of liver. A manganese-requiring isozyme of liver and kidney unaffected by neuraminidase is described, and the locus controlling variation in this isozyme is designated Akp-1. Data from recombinant inbred strains place the locus on chromosome 1 at a distance of 3.6±2.9 cM from the Mls locus on the side distal to the centromere. Test-cross data show the following gene order and recombination percentages: {Mathematical expression} © 1979 Plenum Publishing Corporation.

引用

页码：1093 / 1107

页数：15

共 35 条

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