COMPARISON OF RADIOACTIVE PEPTIDES OBTAINED FROM SPECIFICALLY LABELED HUMAN RENAL AND PLACENTAL ALKALINE-PHOSPHATASES

被引：12

作者：

WHITAKER, KB

MOSS, DW

机构：

来源：

BIOCHEMICAL JOURNAL | 1979年 / 183卷 / 01期

关键词：

D O I：

10.1042/bj1830189

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Peptides with different chromatographic and electrophoretic properties were obtained from human placental and renal alkaline phosphatases by tryptic digestion of the enzymes labelled with radioactive orthophosphate at their active centres. These results provide structural evidence for the distinct genetic origins of the two isoenzymes that had previously been inferred from their different properties and from the observed phenotypic variation of placental phosphatase.

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页码：189 / 192

页数：4

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