PHARMACOLOGICAL MODULATION BY CETIRIZINE AND EBASTINE OF THE CUTANEOUS REACTIVITY TO HISTAMINE

被引：24

作者：

RIVEST, J ^{[1
]}

DESPONTIN, K ^{[1
]}

GHYS, L ^{[1
]}

RIHOUX, JP ^{[1
]}

LACHAPELLE, JM ^{[1
]}

机构：

[1] UNITE DERMATOL PROFESS & ENVIRONNEMENT,UCL 3033,30 CLOS CHAPELLE AUX CHAMPS,B-1200 BRUSSELS,BELGIUM

来源：

DERMATOLOGICA | 1991年 / 183卷 / 03期

关键词：

ANTIHISTAMINE; SKIN PRICK TEST; CETIRIZINE; EBASTINE;

D O I：

10.1159/000247671

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The peripheral H-1-inhibition effects of cetirizine 10 mg and ebastine 10 mg were compared at the skin level after single oral administration. The study was performed in 9 healthy subjects under double-blind randomized crossover conditions. Both drugs were significantly effective up to 24 h. The suppressive effect of cetirizine was significantly more rapid and more marked.

引用

页码：208 / 211

页数：4

共 15 条

[1]

BALTES E, 1988, CHROMATOGRAPHIA, V430, P149

[2] PHARMACOLOGIC MODULATION BY CETIRIZINE 2 HCL AND LORATADINE OF THE HISTAMINE-INDUCED SKIN REACTION IN MICE AND IN HUMANS [J].