THE STRUCTURE OF VELUTINOL-A, AN ANTIINFLAMMATORY COMPOUND WITH A NOVEL PREGNANE SKELETON

被引:21
作者
YUNES, RA
PIZZOLATTI, MG
SANTANA, AEG
HAWKES, GE
CALIXTO, JB
机构
[1] QUEEN MARY & WESTFIELD COLL,DEPT CHEM,MILE END RD,LONDON E1 4NS,ENGLAND
[2] UNIV FED SANTA CATARINA,DEPT QUIM,BR-88040-970 FLORIANOPOLI,SC,BRAZIL
[3] UNIV FED ALAGOAS,DEPT QUIM,BR-57072-970 MACEIO,ALAGOAS,BRAZIL
[4] UNIV FED SANTA CATARINA,DEPT FARMACOL,BR-88040-970 FLORIANOPOLI,SC,BRAZIL
关键词
VELUTINOL-A; ANTI-BRADYKININ; ANTIINFLAMMATORY; STEROID; MANDEVILLA-VELUTINA;
D O I
10.1002/pca.2800040205
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The isolation and purification of velutinol A, a potent anti-inflammatory agent from Mandevilla velutina is reported together with spectroscopic evidence which shows that the structure comprises a novel pregnane skeleton.
引用
收藏
页码:76 / 81
页数:6
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