COMPUTER-AIDED OPTIMIZATION OF GRADIENT MULTIPLE DEVELOPMENT THIN-LAYER CHROMATOGRAPHY .2. MULTISTAGE DEVELOPMENT

被引：19

作者：

MARKOWSKI, W

机构：

[1] Department of Inorganic and Analytical Chemistry, Medical Academy, 20-081 Lublin

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 635卷 / 02期

关键词：

D O I：

10.1016/0021-9673(93)80371-E

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A theoretical model of gradient multiple development is presented as a basis for the optimization of separation by planar multi-step development and automated multiple development (AMD). A computer program for the calculation of final R(F) values for multi-stage development in the gradient mode for known retention vs. eluent composition relationships is reported. The influence of various parameters on the final values of R(F) is discussed. The predicted and experimental R(F) values were compared and showed satisfactory agreement.

引用

页码：283 / 289

页数：7

共 15 条

[1]

Cortes HJ, 1990, MULTIDIMENSIONAL CHR

[2] MODIFICATION OF A HORIZONTAL SANDWICH CHAMBER FOR THIN-LAYER CHROMATOGRAPHY [J].