VOLUME MEASUREMENT OF MULTIPLE-SCLEROSIS LESIONS WITH MAGNETIC-RESONANCE IMAGES - A PRELIMINARY-STUDY

被引：109

作者：

WICKS, DAG ^{[1
]}

TOFTS, PS ^{[1
]}

MILLER, DH ^{[1
]}

DUBOULAY, GH ^{[1
]}

FEINSTEIN, A ^{[1
]}

SACARES, RP ^{[1
]}

HARVEY, I ^{[1
]}

BRENNER, R ^{[1
]}

MCDONALD, WI ^{[1
]}

机构：

[1] INST NEUROL,DEPT COMP & STAT,LONDON WC1N 3BG,ENGLAND

来源：

NEURORADIOLOGY | 1992年 / 34卷 / 06期

关键词：

MAGNETIC RESONANCE IMAGING; VOLUME MEASUREMENT; MULTIPLE SCLEROSIS;

D O I：

10.1007/BF00598953

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The ability to visualise multiple sclerosis lesions in vivo with magnetic resonance imaging suggests an important role in monitoring the course of the disease. In order to help the long-term assessment of prospective treatments, a semi-automated technique for measuring lesion volume has been developed to provide a quantitative index of disease progression. Results are presented from a preliminary study with a single patient and compared to measurements taken from lesion outlines traced by a neuroradiologist, two neurologists and a technician. The semi-automated technique achieved a precision of 6 % compared to a range of 12-33 % for the manual tracing method. It also reduced the human interaction time from at least 60 min to 15 min.

引用

页码：475 / 479

页数：5

共 17 条

[1] STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].