QUANTITATIVE PERIPHERAL COMPUTED TOMODENSITOMETRIC STUDY OF CORTICAL AND TRABECULAR BONE MASS IN RELATION WITH MENOPAUSE

被引:25
作者
RICO, H [1 ]
DIAZ, ERH [1 ]
DURAN, CS [1 ]
VILLA, LF [1 ]
PENELA, SF [1 ]
机构
[1] SANITAS SA, CLIN MUJER, E-28801 MADRID, SPAIN
关键词
QUANTIFIED PERIPHERAL COMPUTED TOMODENSITOMETRY; BONE MASS; POSTMENOPAUSAL BONE LOSS; CORTICAL AND TRABECULAR BONE;
D O I
10.1016/0378-5122(94)90124-4
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Changes in total, cortical and trabecular bone mass were studied using quantitative peripheral computed tomodensitometry on the forearm of 58 normal eugonadal premenopausal women and 116 normal postmenopausal women to evaluate the evolution of bone components with age. In premenopausal women, no changes were seen in any bone component. In postmenopausal women, only trabecular bone mass diminished in the first 5 years after menopause (P < 0.05). It continued to decrease in the next 5 years (P < 0.05), but not later. Cortical bone mass experienced a significant loss 6-10 years after menopause (P < 0.001), and more than 15 years after menopause (P < 0.0005). These results are similar to those obtained with other techniques, and document the differing behavior of the cortical and trabecular bone components with years of menopause.
引用
收藏
页码:183 / 189
页数:7
相关论文
共 27 条
[1]  
DEDEUXCHAISNES CN, 1988, CLIN RHEUM DIS, V12, P559
[2]   HISTOMORPHOMETRIC ANALYSIS OF BONE IN METABOLIC BONE-DISEASE [J].
ERIKSEN, EF ;
STEINICHE, T ;
MOSEKILDE, L ;
MELSEN, F .
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1989, 18 (04) :919-954
[3]  
FOLDES J, 1991, J BONE MINER RES, V6, P759
[4]   METHODOLOGIES FOR THE MEASUREMENT OF BONE-DENSITY AND THEIR PRECISION AND ACCURACY [J].
GOODWIN, PN .
SEMINARS IN NUCLEAR MEDICINE, 1987, 17 (04) :293-304
[5]   DISCRIMINATIVE ABILITY OF TOTAL-BODY BONE-MINERAL MEASURED BY DUAL PHOTON-ABSORPTIOMETRY [J].
GOTFREDSEN, A ;
PODENPHANT, J ;
NILAS, L ;
CHRISTIANSEN, C .
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1989, 49 (02) :125-134
[6]   CURRENT STATUS OF PHYSICAL MEASUREMENTS OF THE SKELETON [J].
GREENFIELD, MA .
MEDICAL PHYSICS, 1992, 19 (06) :1349-1357
[7]  
HENZELL S, 1990, BONE MINER, V10, pS298
[8]  
JOHNELL O, 1987, OSTEOPOROSIS 1987, P150
[9]  
Lindsay R, 1990, Basic Life Sci, V55, P95
[10]   RACIAL-DIFFERENCES IN PREMENOPAUSAL AND POSTMENOPAUSAL BONE HOMEOSTASIS - ASSOCIATION WITH BONE-DENSITY [J].
MEIER, DE ;
LUCKEY, MM ;
WALLENSTEIN, S ;
LAPINSKI, RH ;
CATHERWOOD, B .
JOURNAL OF BONE AND MINERAL RESEARCH, 1992, 7 (10) :1181-1189