THE CHEMISTRY OF CYCLIC TAUTOMERS OF TRYPTOPHAN - TOTAL SYNTHESIS OF (+)-(ENT)-PSEUDOPHRYNAMINOL

被引：21

作者：

CRICH, D

PAVLOVIC, AB

SAMY, R

机构：

[1] University of Illionis at Chicago, Department of Chemistry (M/C111), Chicago, IL 60607-7061

来源：

TETRAHEDRON | 1995年 / 51卷 / 23期

关键词：

D O I：

10.1016/0040-4020(95)00307-T

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A diastereoselective synthesis of the unnatural (+)-enantiomer of the hexahydropyrroloindole alkaloid (-)-pseudophrynaminol (3), isolated from the skin of the Australian frog Pseudophryne coriacea, from a cyclic tautomer (1) of L-tryptophan, is described, The CD spectrum of the synthetic 3 is opposite in sign to that of the natural material enabling the configuration of the natural product to be established as 3aS,8aR.

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页码：6379 / 6384

页数：6

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